Polymorphisms in Th17-related genes and the pathogenesis of autoimmune thyroid disease

Autor:	Yoshinori Iwatani, Takayuki Nobuhara, Mikio Watanabe, Kazuya Takemura, Azusa Okada, Takashi Nanba, Yoh Hidaka, Yuka Katsumata, Takayuki Kunisato, Naoya Inoue, Naoki Omori, Wataru Kobayashi, Yuka Inoue
Rok vydání:	2018
Předmět:	0301 basic medicine endocrine system endocrine system diseases business.industry Immunology Single-nucleotide polymorphism Autoimmune thyroid disease Disease Pathogenesis 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Immunology and Allergy Medicine business Gene
Zdroj:	Autoimmunity. 51(7)
ISSN:	1607-842X
Popis:	The prognosis of autoimmune thyroid disease (AITD) including Graves' disease (GD) and Hashimoto's disease (HD) is difficult to predict. We previously suggested that Th17 cells may be associated with the pathogenesis of AITD. However, the association between gene polymorphisms in Th17-related genes and the prognosis of AITD was not clarified. To clarify this association, we genotyped 12 polymorphisms in 11 Th17-related genes (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967c582ab5f89e14dd45d37a0ae4c1f6 https://pubmed.ncbi.nlm.nih.gov/30474404 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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