Cardiac and Metabolic Effects of Anabolic-Androgenic Steroid Abuse on Lipids, Blood Pressure, Left Ventricular Dimensions, and Rhythm
| Autor: | Suraj Achar, Sanjiv M. Narayan, Armand Rostamian |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Anabolism Heart Ventricles Myocardial Infarction Blood Pressure Left ventricular hypertrophy Article Muscle hypertrophy Anabolic Agents Heart Rate Internal medicine Heart rate medicine Humans Myocardial infarction Adverse effect Doping in Sports Evidence-Based Medicine business.industry Arrhythmias Cardiac Heart medicine.disease Lipids Lipoproteins LDL Blood pressure Athletes Circulatory system Androgens Cardiology Hypertrophy Left Ventricular Lipoproteins HDL Cardiology and Cardiovascular Medicine business |
| Zdroj: | The American Journal of Cardiology. 106:893-901 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2010.05.013 |
| Popis: | Recent surveys and reports suggest that many athletes and bodybuilders abuse anabolic-androgenic steroids (AAS). However, scientific data on the cardiac and metabolic complications of AAS abuse are divergent and often conflicting. A total of 49 studies describing 1,467 athletes were reviewed to investigate the cardiovascular effects of the abuse of AAS. Although studies were typically small and retrospective, some associated AAS abuse with unfavorable effects. Otherwise healthy young athletes abusing AAS may show elevated levels of low-density lipoprotein and low levels of high-density lipoprotein. Although data are conflicting, AAS have also been linked with elevated systolic and diastolic blood pressure and with left ventricular hypertrophy that may persist after AAS cessation. Finally, in small case studies, AAS abuse has been linked with acute myocardial infarction and fatal ventricular arrhythmias. In conclusion, recognition of these adverse effects may improve the education of athletes and increase vigilance when evaluating young athletes with cardiovascular abnormalities. |
| Databáze: | OpenAIRE |
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