Effects of Parenteral Supplementation with Minerals and Vitamins on Oxidative Stress and Humoral Immune Response of Weaning Calves
| Autor: | Esteban Turic, Guillermo Alberto Mattioli, Antonio Humberto Hamad Minervino, Luis Emilio Fazzio, Diana Esther Rosa, Santiago José Raggio, Sebastián Julio Picco |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Antioxidant
medicine.medical_treatment BEEF CALF chemistry.chemical_element medicine.disease_cause Article immune response Immune system Animal science WEIGHT GAIN IMMUNE RESPONSE lcsh:Zoology medicine Weaning oxidative stress lcsh:QL1-991 OXIDATIVE STRESS chemistry.chemical_classification lcsh:Veterinary medicine General Veterinary business.industry Glutathione peroxidase Ciencias Veterinarias weaning Antibody titer weight gain chemistry lcsh:SF600-1100 WEANING Animal Science and Zoology beef calf purl.org/becyt/ford/4.3 [https] medicine.symptom business Weight gain purl.org/becyt/ford/4 [https] Selenium Oxidative stress |
| Zdroj: | Animals Volume 10 Issue 8 Animals, Vol 10, Iss 1298, p 1298 (2020) Animals : an Open Access Journal from MDPI CONICET Digital (CONICET) Consejo Nacional de Investigaciones Científicas y Técnicas instacron:CONICET SEDICI (UNLP) Universidad Nacional de La Plata instacron:UNLP |
| ISSN: | 2076-2615 |
| DOI: | 10.3390/ani10081298 |
| Popis: | We aimed to evaluate the effects of injectable mineral and vitamin supplementation on weaning calves subjected to a low-stress (fence-line) weaning system. Seven-month-old Aberdeen Angus female calves (n = 40, 152 ± 11 kg body weight) from a selenium-deficient area of extensive cattle production on natural grass were randomly assigned to two groups (n = 20 each). One group received subcutaneous supplementation with copper, zinc, selenium, manganese and vitamins A and E (SG), and the other was given sterile saline solution (CG). The animals were supplemented twice, seven days before weaning (day &minus 7) and on the day of weaning (day 0), and they were evaluated 30 (+30) and 60 (+60) days after weaning. Total antioxidant status (TAS), selenium-dependent glutathione peroxidase (GPx) activity, body weight, and average daily gain (ADG) were evaluated. Additionally, antibody titers were assessed prior to and after each immunization with a vaccine containing bovine herpes virus type 1 (BoHV-1). On day +30, body weight (p = 0.03) was higher in SG, whereas TAS (p = 0.02) and GPx (p = 0.0038) activity were lower in CG and remained constant in SG. Antibody titers increased in SG and CG following immunization, being higher in SG on days +30 and +60 (p < 0.05). In conclusion, parenteral supplementation of minerals and vitamins with antioxidant effects in a low-stress weaning system prevented the decrease in TAS and GPx activity, improved antibody response and had positive effects on body weight. |
| Databáze: | OpenAIRE |
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