Staphylococcus aureus mediastinitis following a skin infection in a non‑immunocompromised patient: A case report

Autor: Petros Papalexis, Nikolaos Garmpis, Vasiliki E Georgakopoulou, Nikolaos Trakas, Aikaterini Gkoufa, Panagiotis Drossos, Anna Garmpi, Serafeim Chlapoutakis, Pagona Sklapani, Dimitrios Mermigkis, Christos Damaskos, Xanthi Tsiafaki, Konstantinos Mantzouranis
Rok vydání: 2021
Předmět:
Zdroj: Biomedical Reports
ISSN: 2049-9442
2049-9434
DOI: 10.3892/br.2021.1480
Popis: Mediastinitis is a severe inflammation of the structures located in the mid-chest cavity. Three main causes of infective mediastinitis are traditionally recognized: Deep infection of a sternal wound following cardiothoracic surgery, perforation of the esophagus, and the descending necrotizing mediastinitis as a result of odontogenic, pharyngeal or cervical infections. Mediastinitis, as a complication of skin infection with hematogenous spread is infrequent. Methicillin-resistant Staphylococcus aureus (MRSA) is a gram-positive bacteria, and is responsible for numerous severe infections. MRSA mediastinitis is a rare infection and is typically associated with complications of sternotomy and retropharyngeal abscesses. Here, the second known case of mediastinitis of a hematogenous origin in a non-immunocompromised 41-year-old patient following primary skin infection, accompanied by sternal osteomyelitis, lung consolidation and pleural effusion is described; MRSA was the responsible pathogen. The clinical course was favorable after 6 weeks of antibiotics administration without drainage or surgical intervention.
Databáze: OpenAIRE