Staphylococcus aureus mediastinitis following a skin infection in a non‑immunocompromised patient: A case report
Autor: | Petros Papalexis, Nikolaos Garmpis, Vasiliki E Georgakopoulou, Nikolaos Trakas, Aikaterini Gkoufa, Panagiotis Drossos, Anna Garmpi, Serafeim Chlapoutakis, Pagona Sklapani, Dimitrios Mermigkis, Christos Damaskos, Xanthi Tsiafaki, Konstantinos Mantzouranis |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Pleural effusion business.industry General Neuroscience Osteomyelitis staphylococcal skin infection Perforation (oil well) osteomyelitis Articles General Medicine methicillin-resistant Staphylococcus aureus Skin infection medicine.disease medicine.disease_cause Methicillin-resistant Staphylococcus aureus Mediastinitis General Biochemistry Genetics and Molecular Biology Surgery Cardiothoracic surgery Staphylococcus aureus medicine General Pharmacology Toxicology and Pharmaceutics business mediastinitis |
Zdroj: | Biomedical Reports |
ISSN: | 2049-9442 2049-9434 |
DOI: | 10.3892/br.2021.1480 |
Popis: | Mediastinitis is a severe inflammation of the structures located in the mid-chest cavity. Three main causes of infective mediastinitis are traditionally recognized: Deep infection of a sternal wound following cardiothoracic surgery, perforation of the esophagus, and the descending necrotizing mediastinitis as a result of odontogenic, pharyngeal or cervical infections. Mediastinitis, as a complication of skin infection with hematogenous spread is infrequent. Methicillin-resistant Staphylococcus aureus (MRSA) is a gram-positive bacteria, and is responsible for numerous severe infections. MRSA mediastinitis is a rare infection and is typically associated with complications of sternotomy and retropharyngeal abscesses. Here, the second known case of mediastinitis of a hematogenous origin in a non-immunocompromised 41-year-old patient following primary skin infection, accompanied by sternal osteomyelitis, lung consolidation and pleural effusion is described; MRSA was the responsible pathogen. The clinical course was favorable after 6 weeks of antibiotics administration without drainage or surgical intervention. |
Databáze: | OpenAIRE |
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