Imbalance of naive and memory T lymphocytes with sustained high cellular activation during the first year of life from uninfected children born to HIV-1-infected mothers on HAART
| Autor: | M.I. de Moraes-Pinto, Daisy Maria Machado, Erika Ono, Daniela Souza Araújo de Angelis, Reinaldo Salomão, A.M. Nunes dos Santos, Esper G. Kallas, R.C. de Menezes Succi |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Immunological stimulation Physiology T-Lymphocytes HIV Infections CD38 Lymphocyte Activation Biochemistry Gastroenterology Immunophenotyping Pregnancy Antiretroviral Therapy Highly Active Medicine General Pharmacology Toxicology and Pharmaceutics Pregnancy Complications Infectious lcsh:QH301-705.5 lcsh:R5-920 General Neuroscience General Medicine Viral Load Fetal Blood Flow Cytometry In utero Prenatal Exposure Delayed Effects Gestation Female lcsh:Medicine (General) Viral load Adult medicine.medical_specialty Adolescent Immunology Biophysics Young Adult Highly active antiretroviral therapy Immune system Internal medicine Humans business.industry Infant Cell Biology Neonates of HIV-infected mothers medicine.disease Blood Cell Count lcsh:Biology (General) Case-Control Studies HIV-1 business Immunologic Memory CD8 |
| Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 41, Iss 8, Pp 700-708 (2008) Brazilian Journal of Medical and Biological Research v.41 n.8 2008 Brazilian Journal of Medical and Biological Research Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC Scopus-Elsevier Brazilian Journal of Medical and Biological Research, Volume: 41, Issue: 8, Pages: 700-708, Published: AUG 2008 |
| ISSN: | 1414-431X |
| Popis: | The immune consequences of in utero HIV exposure to uninfected children whose mothers were submitted to highly active antiretroviral therapy (HAART) during gestation are not well defined. We evaluated 45 HIV-exposed uninfected (ENI) neonates and 45 healthy unexposed control (CT) neonates. All HIV-infected mothers received HAART during pregnancy, and the viral load at delivery was |
| Databáze: | OpenAIRE |
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