Factors influencing the quality of total mesorectal excision

Autor: Ingo Gastinger, Hans Lippert, Benjamin Garlipp, Henry Ptok, H. Scheidbach, Uwe Schmidt, Frank Meyer, P Stübs
Rok vydání: 2012
Předmět:
Zdroj: British Journal of Surgery. 99:714-720
ISSN: 1365-2168
0007-1323
Popis: Background Total mesorectal excision (TME) has become the standard of care for rectal cancer. Incomplete TME may lead to local recurrence. Methods Data from the multicentre observational German Quality Assurance in Rectal Cancer Trial were used. Patients undergoing low anterior resection for rectal cancer between 1 January 2005 and 31 December 2009 were included. Multivariable analysis using a stepwise logistic regression model was performed to identify predictors of suboptimal TME. Results From a total of 6179 patients, complete data sets for 4606 patients were available for analysis. Pathological tumour category higher than T2 (pT3 versus pT1/2: odds ratio (OR) 1·22, 95 per cent confidence interval 1·01 to 1·47), tumour distance from the anal verge less than 8 cm (OR 1·27, 1·05 to 1·53), advanced age (65–80 years: OR 1·25, 1·03 to 1·52; over 80 years: OR 1·60, 1·15 to 2·22), presence of intraoperative complications (OR 1·63, 1·15 to 2·30), monopolar dissection technique (OR 1·43, 1·14 to 1·79) and low case volume (fewer than 20 procedures per year) of the operating surgeon (OR 1·20, 1·06 to 1·36) were independently associated with moderate or poor TME quality. Conclusion TME quality was influenced by patient- and treatment-related factors.
Databáze: OpenAIRE
Externí odkaz: