Can we predict new AF occurrence in single-chamber ICD patients? Insights from an observational investigation
| Autor: | Giuseppe Boriani, Giovanni Luca Botto, Maurizio Lunati, Mauro Biffi, T Infusino, Renato Pietro Ricci, Alessandro Capucci, Saverio Iacopino, Giovanni Morani, Domenico Facchin, Matteo Ziacchi, Luigi Padeletti, Stefano Bianchi, Maurizio Landolina |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Time Factors Population Atrial fibrillation Atrial fibrillation diagnosis single chamber defibrillator CHADS2 score Medicine (all) Cardiology and Cardiovascular Medicine 030204 cardiovascular system & hematology New onset 03 medical and health sciences 0302 clinical medicine Recurrence Internal medicine Atrial Fibrillation Humans Medicine In patient Heart Atria Prospective Studies 030212 general & internal medicine education Prospective cohort study education.field_of_study business.industry Incidence Incidence (epidemiology) Middle Aged Prognosis medicine.disease Defibrillators Implantable Italy Female Observational study business Follow-Up Studies Single chamber |
| Zdroj: | International Journal of Cardiology. 230:275-280 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/j.ijcard.2016.12.126 |
| Popis: | Background Atrial tachyarrhythmias (AT/AF) have been associated with an increased risk of mortality, morbidity and ischemic stroke. Up to now, single chamber ICD diagnostics was not able to detect AT/AF, therefore the incidence of new onset AT/AF in patients with single chamber ICD is not known. Objective To evaluate incidence and predictors of AT/AF occurrence in patients with dual-chamber ICD with no pacing indications and no history of AT/AF that strictly mimic single chamber ICD recipient. Methods & results Consecutive dual-chamber ICD patients were prospectively followed by 47 Italian cardiologic centers in an observational research. Clinical and device data were reviewed by expert cardiologists to assess AT/AF occurrence. Multivariate regression analysis evaluated the risk of new-onset AT/AF and its association with patients' baseline characteristics and with CHADS 2 score. 428 (13.4% female, 64years old) patients were followed for a median observation period of 31months. AT/AF episodes occurred in 160 (37.4%) patients when considering at least 5min duration, in 95 (22.2%) for AT/AF ≥6h, in 47 (11.0%) for AT/AF ≥1day, in 29 (6.8%) for AT/AF ≥7days. Patients with CHADS 2 ≥2, who comprised 36% of the whole population, showed higher incidence of AT/AF ≥6h compared with patients with CHADS 2 p =0.011). Conclusions Our observations in a population of dual-chamber ICD patients with no pacing indications and no history of AT/AF, who strictly mimic single–chamber ICD recipients, highlight that AT/AF episodes occurred in the 37.5% of the population and CHADS 2 score is predictive of new-onset AT/AF. |
| Databáze: | OpenAIRE |
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