Recent advances on tea polyphenols
| Autor: | Congde Huo, Imthiyaz Mohammad, Jyoti Kanwar, Mujtaba Taskeen, Qing Ping Dou, Tak Hang Chan |
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| Předmět: |
Clinical Trials as Topic
Tea General Immunology and Microbiology Traditional medicine business.industry Green Tea Polyphenols Polyphenols food and beverages Cancer Health benefits Green tea medicine.disease complex mixtures Article General Biochemistry Genetics and Molecular Biology Polyphenol Active compound medicine Molecular targets Anticarcinogenic Agents Humans heterocyclic compounds sense organs business |
| Zdroj: | Scopus-Elsevier |
| Popis: | Over the past decade many scientific and medical studies have focused on green tea for its long-purported health benefits. There is convincing evidence that tea is a cup of life. It has multiple preventive and therapeutic effects. This review thus focuses on the recent advances of tea polyphenols and their applications in the prevention and treatment of human cancers. Of the various polyphenols in tea, (-)-Epigallocatechin-3-gallate (EGCG) is the most abundant, and active compound studied in tea research. EGCG inhibits several molecular targets to inhibit cancer initiation and modulates several essential survival pathways to block cancer progression. Herein, we describe the various mechanisms of action of EGCG and also discuss previous and current ongoing clinical trials of EGCG and green tea polyphenols in different cancer types. |
| Databáze: | OpenAIRE |
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