Mathematical Modeling of Transport and Degradation of Feedstuffs in the Small Intestine

Autor: Masoomeh Taghipoor, Jean-René Licois, Guy Barles, Philippe Lescoat, Christine Georgelin
Přispěvatelé: Laboratoire de Mathématiques et Physique Théorique (LMPT), Université de Tours-Centre National de la Recherche Scientifique (CNRS), Recherches Avicoles (SRA), Institut National de la Recherche Agronomique (INRA), Fédération de recherche Denis Poisson (FDP), Université d'Orléans (UO)-Université de Tours-Centre National de la Recherche Scientifique (CNRS), Projet CaSciModOT, Cluster de la Région Centre, PEPS CNRS-INRA, PEPS CNRS-INRA 'Comprehension et Modelisation du devenir de l'aliment dans le tube digestif', Centre National de la Recherche Scientifique (CNRS)-Université de Tours, Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Unité de Recherches Avicoles (URA), Université d'Orléans (UO)-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Taghipoor, Masoomeh
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Swine
030309 nutrition & dietetics
Dynamical Systems (math.DS)
modélisation métabolique
Intestine
Small
Mathematics - Dynamical Systems
Tissues and Organs (q-bio.TO)
0303 health sciences
Applied Mathematics
General Medicine
medicine.anatomical_structure
Biochemistry
Biological Physics (physics.bio-ph)
Modeling and Simulation
Ordinary differential equation
Small Intestine
Animal Nutritional Physiological Phenomena
Digestion
digestion intestinale
Bolus (digestion)
General Agricultural and Biological Sciences
Biological system
Enzymatic degradation
Statistics and Probability
[MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS]
FOS: Physical sciences
Transport
animal monogastrique
Biology
System of linear equations
Models
Biological
General Biochemistry
Genetics and Molecular Biology
03 medical and health sciences
modèle mathématique
oiseau
FOS: Mathematics
medicine
Animals
Physics - Biological Physics
030304 developmental biology
General Immunology and Microbiology
Modeling
Quantitative Biology - Tissues and Organs
Enzymatic Degradation
Small intestine
digestion
small intestine
modeling
ordinary differential equations
transport
Intestinal Absorption
Ordinary Differential Equations
adsorption
FOS: Biological sciences
Gastrointestinal Motility
[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
Zdroj: Journal of Theoretical Biology
Journal of Theoretical Biology, Elsevier, 2012, pp.Journal of Theoretical Biology 294 (2012) 114-121. ⟨10.1016/j.jtbi.2011.10.024⟩
Journal of Theoretical Biology, Elsevier, 2012, 294, pp.Journal of Theoretical Biology 294 (2012) 114-121. ⟨10.1016/j.jtbi.2011.10.024⟩
Journal of Theoretical Biology (294), 114-121. (2012)
ISSN: 0022-5193
1095-8541
DOI: 10.1016/j.jtbi.2011.10.024⟩
Popis: We describe a mathematical model of digestion in the small intestine. The main interest of our work is to consider simultaneously the different aspects of digestion i.e. transport of the bolus all along the intestine, feedstuffs degradation according to the enzymes and local physical conditions, and nutrients absorption. A system of coupled ordinary differential equations is used to model these phenomena. The major unknowns of this system are the position of the bolus and its composition. This system of equations is solved numerically. We present several numerical computations for the degradation, absorption and transport of the bolus with acceptable accuracy regarding the overall behavior of the model and also when challenged versus experimental data. The main feature and interest of this model are its genericity. Even if we are at an early stage of development, our approach can be adapted to deal with contrasted feedstuffs in non-ruminant animal to predict the composition and velocity of bolus in the small intestine.
Databáze: OpenAIRE
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