Advances in the Endoscopic Diagnosis of Barrett Esophagus
| Autor: | Ashley H. Davis-Yadley, Mokenge P. Malafa, Luis R Pena, Kevin G Neill |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Image-Guided Biopsy
medicine.medical_specialty Esophageal Neoplasms MEDLINE Adenocarcinoma Barrett Esophagus 03 medical and health sciences 0302 clinical medicine Risk Factors Biomarkers Tumor medicine Humans Prospective Studies Risk factor Esophagus Prospective cohort study Early Detection of Cancer business.industry Hematology General Medicine medicine.disease medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Gastroesophageal Reflux 030211 gastroenterology & hepatology Esophagoscopy Radiology business Precancerous Conditions Tomography Optical Coherence |
| Zdroj: | Cancer Control. 23:67-77 |
| ISSN: | 1073-2748 |
| DOI: | 10.1177/107327481602300112 |
| Popis: | Background Barrett esophagus (BE) continues to be a major risk factor for developing esophageal adenocarcinoma. Methods We review the risk factors, diagnosis, and management of BE, with an emphasis on the most current endoscopic diagnostic modalities for BE. Results Novel diagnostic modalities have emerged to address the inadequacies of standard, untargeted biopsies, such as dye-based and virtual chromoendoscopy, endoscopic mucosal resection, molecular biomarkers, optical coherence tomography, confocal laser endomicroscopy, volumetric laser endomicroscopy, and endocytoscopy. Treatment of BE depends on the presence of intramucosal cancer or dysplasia, particularly high-grade dysplasia with or without visible mucosal lesions. Conclusions Recent advances in endoscopic diagnostic tools demonstrate promising results and help to mitigate the shortcomings of the Seattle protocol. Future research as well as refining these tools may help aid them in replacing standard untargeted biopsies. |
| Databáze: | OpenAIRE |
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