Vitamin D and COVID-19: An Overview of Recent Evidence
| Autor: | Aya Mousa, Drishti Ghelani, Simon Alesi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
QH301-705.5
SARS-CoV-2 coronavirus vitamin D Context (language use) Review Disease Adaptive Immunity Bioinformatics medicine.disease_cause Catalysis Inorganic Chemistry Immunity Pandemic Vitamin D and neurology Animals Humans Immunologic Factors Medicine Biology (General) Physical and Theoretical Chemistry QD1-999 Molecular Biology Spectroscopy Coronavirus business.industry Organic Chemistry COVID-19 Outbreak Vitamins General Medicine Acquired immune system immunity Immunity Innate infection Computer Science Applications Chemistry business |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 22, Iss 10559, p 10559 (2021) |
| ISSN: | 1422-0067 |
| Popis: | The novel coronavirus severe acute respiratory syndrome (SARS-CoV-2) has progressed rapidly from an outbreak to a global pandemic, with new variants rapidly emerging. Coronavirus disease 2019 (COVID-19), the disease resulting from SARS-CoV-2 infection, can lead to multiorgan damage. Due to the extremely contagious and fatal nature of the virus, it has been a priority of medical research to find effective means of treatment. Amid this search, the role of vitamin D in modulating various aspects of the innate and adaptive immune system has been discussed. This review aims to consolidate the research surrounding the role of vitamin D in the treatment and prevention of COVID-19. While there are some conflicting results reported, the consensus is that vitamin D has a host of immunomodulatory effects which may be beneficial in the context of COVID-19 and that low levels of vitamin D can result in dysfunction of crucial antimicrobial effects, potentially contributing to poor prognosis. Studies also show that the effects of low vitamin D can be mitigated via supplementation, although the benefits of vitamin D supplementation in the treatment of COVID-19 remain controversial. |
| Databáze: | OpenAIRE |
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