Natural and Experimental Aujeszky's Disease Virus Hepatitis in the Neonatal Calf
| Autor: | Freddy Haesebrouck, Richard Ducatelle, D. Maenhout, J. Nuytten, C. Miry, J. Hoorens |
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| Rok vydání: | 1986 |
| Předmět: |
Pathology
medicine.medical_specialty Cattle Diseases Autopsy Disease Umbilical cord Virus Acute illness Pathogenesis Necrosis medicine Animals Hepatitis Pseudorabies Immunoperoxidase business.industry General Medicine medicine.disease Virology medicine.anatomical_structure Animals Newborn Liver Hepatitis Viral Animal Cattle Female business |
| Zdroj: | Journal of Veterinary Medicine, Series B. 33:502-507 |
| ISSN: | 1439-0450 0931-1793 |
| DOI: | 10.1111/j.1439-0450.1986.tb00061.x |
| Popis: | Summary Two young calves suffering from an acute illness were presented at the Veterinary Faculty. One had nervous signs, the other had colic. Both calves died within one day. At autopsy, greyisch-white spots were found on the liver. Histologically, these spots were necrotic foci with intranuclear inclusion bodies at their periphery. Immunoperoxidase study and virological examination clearly proved the association of the lesions with multiplication of Aujeszky's disease virus. Clinical signs and liver lesions could be reproduced after experimental infection in a neonatal calf via the umbilical cord with the virus strain from one of the naturally infected calves. The present findings were discussed in view of the epidemiology and pathogenesis of Aujeszky's disease in cattle. Zusammenfassung Zwei junge Kalber zeigten nervose Storungen, Kolik, und starben innerhalb einen Tag nach dem Beginn der Symptome. Bei Autopsie fand man verschiedene grauweise Nekroseherdchen in der Leber. Histologisch konnte man in diesem Nekroseherdchen intranukleare Inklusionen nachweisen. Virologische und immunhistochemische Untersuchung war positiv fur Aujeszkyvirus. Experimentelle Infektion mit dem isolierten Virusstamm im Nabel bei einem Neonatus-Kalb resultierte in eine fatale Aujeszkysche Krankheit mit Nekroseherdchen in der Leber. Die Autoren ziehen die Aufmerksamkeit auf die omphalogene Aujeszkyvirus-Infektion bei Neonatikalbern. |
| Databáze: | OpenAIRE |
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