Treatment of articular cartilage lesions of the knee joint using a modified AMIC technique
| Autor: | Mariano Giuseppe Di Salvatore, Carmine Latte, Luciano Liguori, Antonio Pascarella, Riccardo Ciatti, Fabio Pascarella, Germano Iannella |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Knee Joint Knee Injuries Mesenchymal Stem Cell Transplantation Lesion Young Adult Chondrocytes medicine Humans Regeneration Orthopedics and Sports Medicine Bone Marrow Transplantation business.industry Regeneration (biology) Cartilage Mesenchymal stem cell Middle Aged Magnetic Resonance Imaging Autologous matrix-induced chondrogenesis medicine.anatomical_structure Surgery Female Bone marrow Collagen medicine.symptom Stem cell business Follow-Up Studies |
| Zdroj: | Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 18(4) |
| ISSN: | 1433-7347 |
| Popis: | This study describes a modified AMIC technique consisting of perforations according to Pridie, rather than microfractures, and the covering of the focus of the lesion with a biological collagen patch enriched with bone marrow blood drawn through the knee itself. This technique allows advantages of both the Pridie technique and the in situ proliferation of mesenchymal cells beneath a biological collagen membrane, ‘augmented’, with bone marrow blood. The collagen membrane forms the roof of a ‘biological chamber’, and serves to protect and contains the stem cells as they differentiate into chondrocytes, which will form a healthy regenerative cartilage. |
| Databáze: | OpenAIRE |
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