Future perspectives on the use of deformation analysis to identify the underlying pathophysiological basis for cardiovascular compromise in neonates
| Autor: | Neidin Bussmann, Afif El-Khuffash |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Systemic blood Systole Population Cardiac metabolism Blood Pressure Gestational Age Infant Premature Diseases 03 medical and health sciences 0302 clinical medicine Diastole 030225 pediatrics medicine Humans Cardiovascular instability Image acquisition Myocytes Cardiac Cardiac Output Hypoxia Brain Intensive care medicine education education.field_of_study Cellular metabolism business.industry Myocardium Infant Newborn Heart Myocardial Contraction Elasticity Echocardiography Pediatrics Perinatology and Child Health Vascular Resistance business Infant Premature 030217 neurology & neurosurgery |
| Zdroj: | Pediatric Research. 85:591-595 |
| ISSN: | 1530-0447 0031-3998 |
| DOI: | 10.1038/s41390-019-0293-z |
| Popis: | The assessment of the wellbeing of the cardiovascular status in premature infants has come to the forefront in recent years. There is an increasing realisation that myocardial performance, systemic blood flow and end-organ perfusion (particularly during the transitional period) play an important role in determining short and long-term outcomes in this population. The recent open access series on Neonatologist Performed Echocardiography (NPE) published in this journal outline the necessary techniques for image acquisition and analysis and provide a framework for the potential clinical applications of NPE in neonatal, and specifically preterm care. In this "Future Perspectives" review, we describe the important determinants of adequate cellular metabolism and myocardial performance (e.g. loading conditions, intrinsic contractility and morphological change), we discuss the maladaptive state of the preterm cardiovascular system, and highlight the emerging role that non-invasive echocardiography techniques, such as deformation analysis, serve in identifying the underlying physiological basis for cardiovascular instability. |
| Databáze: | OpenAIRE |
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