Morphometric and histomorphometric evaluations of high-purity macro/microporous beta-tricalcium phosphate in maxillary sinus floor elevation: preliminary results on a retrospective, multi-center, observational study
| Autor: | Atsushi Fujita, Tomonori Hasegawa, Hitoshi Kawamata, Chonji Fukumoto, Yuta Sawatani |
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| Rok vydání: | 2021 |
| Předmět: |
Calcium Phosphates
High-purity macro/microporous β-TCP Maxillary sinus medicine.medical_treatment Sinus Floor Augmentation Dentistry Augmentation Bone grafting Maxillary sinus floor elevation Beta-tricalcium phosphate Maxilla medicine Humans Dental implant General Dentistry Sinus (anatomy) Dental alveolus Retrospective Studies Bone Transplantation business.industry Dental Implantation Endosseous RK1-715 Maxillary Sinus medicine.anatomical_structure Bone Substitutes Oral and maxillofacial surgery business Research Article |
| Zdroj: | BMC Oral Health, Vol 21, Iss 1, Pp 1-9 (2021) BMC Oral Health |
| ISSN: | 1472-6831 |
| Popis: | BackgroundThe present study examined the effectiveness of high-purity macro/microporous beta-tricalcium phosphate (HPMM β-TCP) as a bone grafting material for maxillary sinus floor elevation by morphometric, histopathological, and histomorphometric evaluations.MethodsTen unilateral maxillary sinus floor elevation procedures using 100% HPMM β-TCP were performed in 10 patients. Morphometric evaluation was carried out by computed tomography (CT) imaging immediately after augmentation and prior to dental implant placement 7 months later. Histopathological and histomorphometric evaluations were carried out by bone biopsy retrieval at the time of dental implant placement 7 months after sinus floor elevation.ResultsAll 10 sinus floor elevations were successful. Morphometric evaluation by CT showed that the vertical height and volume gained by sinus floor elevation decreased 7 months after surgery. Histopathological evaluation of bone biopsy retrieval specimens showed no signs of inflammation at the newly formed bone area and the native alveolar bone area. New bone formation was observed at the cranial side from the native alveolar bone. The newly formed bone had a trabecular structure and was in intimate contact with the HPMM β-TCP material. Histomorphometric evaluation of bone biopsy retrieval specimens showed an average new bone volume of 33.97% ± 2.79% and an average residual HPMM β-TCP volume of 15.81% ± 4.52%.ConclusionsIn this study, HPMM β-TCP showed osteoconductive properties for vertical augmentation of the atrophied maxilla by means of a maxillary sinus floor elevation procedure allowing subsequent dental implant placement after a 7-month healing period. |
| Databáze: | OpenAIRE |
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