Effect of Dopamine on Hypotension Induced by Spinal Anesthesia
| Autor: | Charles R. Brinkman, B. Nuwayhid, T. Cabalum, Stephen M. Lieb, Marcelo Zugaib, Nicholas S. Assali |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Tetracaine
Dopamine Pregnancy Complications Cardiovascular Blood Pressure Anesthesia Spinal Heart Rate Pregnancy Heart rate Animals Medicine Infusions Parenteral Sheep business.industry Uterus Obstetrics and Gynecology Blood flow Blockade Peripheral medicine.anatomical_structure Blood pressure Regional Blood Flow Depression Chemical Anesthesia Circulatory system Vascular resistance Female Vascular Resistance Hypotension business Autonomic Nerve Block medicine.drug |
| Zdroj: | Survey of Anesthesiology. 24:112 |
| ISSN: | 0039-6206 |
| DOI: | 10.1097/00132586-198004000-00053 |
| Popis: | Chronically instrumented, near-term pregnant sheep were subjected to autonomic blockade with spinal anesthesia. Systemic arterial pressure, heart rate, and uterine blood flow decreased and uterine vascular resistance increased during the spinal blockade. Infusion of dopamine during the spinal hypotension corrected the disturbed circulatory parameters. These data provide evidence that: (1) the peripheral circulation of the near-term pregnant sheep is as sensitive as that of pregnant women to autonomic blockade, (2) the sensitivity is probably related to factors other than the changes in venous pressure in areas below the pelvis, and (3) dopamine represents a useful agent in the management of spinal hypotension. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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