Descemet's Membrane Endothelial Keratoplasty in South Asian Population
| Autor: | Prateek Chougale, Jagdeesh K. Reddy, Vipul Bhandari |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Corneal endothelium genetic structures South asian population Corneal Endothelium Descemet′s Membrane Descemet′s Membrane Endothelial Keratoplasty 03 medical and health sciences 0302 clinical medicine lcsh:Ophthalmology Descemet's Membrane Ophthalmology medicine Best corrected visual acuity business.industry eye diseases Surgery Descemet's membrane endothelial keratoplasty Descemet's membrane Endothelial cell density medicine.anatomical_structure lcsh:RE1-994 030221 ophthalmology & optometry Descemet's Membrane Endothelial Keratoplasty Original Article sense organs business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Ophthalmic & Vision Research Journal of Ophthalmic & Vision Research, Vol 11, Iss 4, Pp 368-371 (2016) |
| ISSN: | 2008-2010 |
| Popis: | Purpose: To evaluate visual outcomes, endothelial cell density and complications following Descemet's membrane endothelial keratoplasty (DMEK). Methods: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuity (BCVA) and endothelial cell density (ECD) were measured and compared before and 6 months after surgery. Results: Out of 40 eyes, 34 eyes (85%) had BCVA ranging from 0.5 to 0.7 LogMAR 6 months postoperatively. Mean donor ECD was 2367.96 ± 47.87 (range, 2314.0-2472.0) cells/mm 2 preoperatively, which was reduced to 1798.42 ± 45.79 (range, 1736.0-1902.0) cells/mm 2 6 months after DMEK surgery, indicating a mean reduction of 569.54 cells/mm 2 (24%) in ECD. Conclusion: DMEK is an emerging and a more advanced alternative to penetrating keratoplasty (PKP) and Descemet's stripping endothelial keratoplasty (DSEK) for corneal pathologies involving the corneal endothelium. Compared to PK and DSEK, however, DMEK has a longer learning curve, and its safety and efficacy need to be confirmed through more experience on a large volume of cases. |
| Databáze: | OpenAIRE |
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