Plasmodium vivax hospitalizations in a monoendemic malaria region: severe vivax malaria?
| Autor: | Edith Guerrero, Kimberly A. Edgel, Paul C. F. Graf, G. Christian Baldeviano, Edwar Pozo, Antonio M. Quispe, Andres G. Lescano, Salomón Durand |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Pediatrics Endemic Diseases Plasmodium vivax Severity of Illness Index Peru Aged 80 and over biology Transmission (medicine) Lung Injury/diagnosis/etiology/parasitology/pathology Age Factors Brain Anemia Shock Lung Injury Middle Aged Hospitalization Renal Insufficiency Chronic/diagnosis/etiology/parasitology/pathology Infectious Diseases Editorial Cerebral Malaria Brain/parasitology/pathology Child Preschool Shock/diagnosis/etiology/parasitology/pathology Female Malaria Vivax/complications/diagnosis/parasitology/pathology purl.org/pe-repo/ocde/ford#3.03.06 [https] Adult medicine.medical_specialty Critical Illness Lung injury Anemia/diagnosis/etiology/parasitology/pathology Virology Severity of illness parasitic diseases medicine Malaria Vivax Humans Renal Insufficiency Chronic Plasmodium vivax/pathogenicity Aged Hospitalization/statistics & numerical data Retrospective Studies business.industry Retrospective cohort study medicine.disease biology.organism_classification Surgery Case-Control Studies Parasitology business Malaria |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene |
| Popis: | Severe malaria caused by Plasmodium vivax is no longer considered rare. To describe its clinical features, we performed a retrospective case control study in the subregion of Luciano Castillo Colonna, Piura, Peru, an area with nearly exclusive vivax malaria transmission. Severe cases and the subset of critically ill cases were compared with a random set of uncomplicated malaria cases (1:4). Between 2008 and 2009, 6,502 malaria cases were reported, including 106 hospitalized cases, 81 of which fit the World Health Organization definition for severe malaria. Of these 81 individuals, 28 individuals were critically ill (0.4%, 95% confidence interval = 0.2-0.6%) with severe anemia (57%), shock (25%), lung injury (21%), acute renal failure (14%), or cerebral malaria (11%). Two potentially malaria-related deaths occurred. Compared with uncomplicated cases, individuals critically ill were older (38 versus 26 years old, P < 0.001), but similar in other regards. Severe vivax malaria monoinfection with critical illness is more common than previously thought. |
| Databáze: | OpenAIRE |
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