Assessment of colonic contents in patients with chronic constipation using MRI
| Autor: | Koji Fujita, A. Nakajima, Takuma Higurashi, Yumi Inoh, Kenji Kanoshima, Taro Takahara, Kazumasa Hiroishi, Akiko Fuyuki, Kanji Ohkuma, Shiori Uchiyama, Hajime Nagase, Akihiko Kusakabe, Hiroshi Iida, Takashi Nonaka, Hidenori Ohkubo, Masahiko Inamori |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Constipation Nausea GSRS Clinical Biochemistry Medicine (miscellaneous) Rectum Gastroenterology Descending colon 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Chronic constipation Nutrition and Dietetics nausea and diarrhea business.industry Sigmoid colon constipation digestive system diseases Diarrhea medicine.anatomical_structure 030220 oncology & carcinogenesis Defecation 030211 gastroenterology & hepatology Original Article medicine.symptom business MRI |
| Zdroj: | Journal of Clinical Biochemistry and Nutrition |
| ISSN: | 0912-0009 0000-2127 |
| Popis: | Although chronic constipation is common, colonic functional evaluating tests are uncommon. This study examines whether chronic constipation and gastrointestinal symptoms are correlated with the lateral diameter of the colon measured from MRI images. We included chronic constipation patients in a prospective, cross-sectional study using MRI at three centers. We divided 3D MRI colorectal images into 6 segments using with specified sequences and selected the maximum luminal diameter from each segment. We used the GSRS questionnaire to evaluate gastrointestinal symptoms. We evaluated the correlation between luminal diameters and GSRS scores. We found the following positive correlations: descending colon and unsatisfactory defecation symptoms; sigmoid colon and diarrhea; and rectum and constipation. The sum and ratio of the ascending and sigmoid colon diameters correlated with nausea and diarrhea. The sum of the transvers to the sigmoid colon diameter also correlated with nausea and diarrhea. The sum of all segment diameters correlated with nausea and constipation. In conclusion, we showed cross-sectional study of colonic MRI correlate with gastrointestinal symptoms. MRI might be useful for colonic motility evaluations to determine appropriate constipation treatments (Clinical trial registry number UMIN 000021274). |
| Databáze: | OpenAIRE |
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