Transferrin predicts outcome in patients who underwent liver resection for colorectal liver metastases
| Autor: | Koichiro Haruki, Hironori Shiozaki, Takeshi Gocho, Tomotaka Kumamoto, Kenei Furukawa, Toru Ikegami, Tomohiko Taniai, Ryoga Hamura, Shinji Onda, Jungo Yasuda, Yoshihiro Shirai |
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| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty Multivariate analysis Hepatic resection medicine.medical_treatment Preoperative care Gastroenterology Internal medicine medicine Hepatectomy Humans Radiology Nuclear Medicine and imaging In patient Retrospective Studies chemistry.chemical_classification business.industry Liver Neoplasms Transferrin General Medicine Odds ratio Prognosis Confidence interval Oncology chemistry Neoplasm Recurrence Local Colorectal Neoplasms business |
| Zdroj: | Japanese Journal of Clinical Oncology. 51:1400-1406 |
| ISSN: | 1465-3621 |
| DOI: | 10.1093/jjco/hyab096 |
| Popis: | Introduction The aim of this study is to investigate the relationship between preoperative serum transferrin level and long-term outcomes in patients with colorectal liver metastases after hepatic resection. Methods We retrospectively investigated 72 patients who underwent hepatic resection for colorectal liver metastases and explored the relationship between serum transferrin level and long-term outcomes. Results In multivariate analysis, H3 (odds ratio 3.43, 95% confidence interval 1.11–10.89 and P = 0.03) was an independent and significant predictor of the disease-free survival, and a transferrin level ≥ 190 mg/dl (odds ratio 0.20, 95% confidence interval 0.05–0.79 and P = 0.02) and the time to recurrence after hepatectomy Conclusions The serum transferrin level is a useful predictor of poor overall survival in patients with colorectal liver metastases after hepatic reaction. |
| Databáze: | OpenAIRE |
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