Pancreatic Tissue Fluid Pressure in Chronic Pancreatitis Relation to Pain, Morphology, and Function

Autor: Madsen P, L. Borly, Rasmussen Sg, N Ebbehøj, A Owre, J Bülow, Peter Matzen
Rok vydání: 1990
Předmět:
Zdroj: Scandinavian Journal of Gastroenterology. 25:1046-1051
ISSN: 1502-7708
0036-5521
DOI: 10.3109/00365529008997633
Popis: The relation between pancreatic tissue fluid pressure and pain, morphology, and function was studied in a cross-sectional investigation. Pressure measurements were performed by percutaneous fine-needle puncture. Thirty-nine patients with chronic pancreatitis were included, 25 with pain and 14 without pain. The pressure was higher in patients with pain than in patients without pain (p = 0.000001), and this was significantly related to a pain score from a visual analogue scale (p less than 0.001). Patients with pancreatic pseudocysts had both higher pressure and higher pain score than patients without (p = 0.004 and p = 0.0003, respectively). The pressure was significantly related (inversely) to pancreatic duct diameter only in the group of 19 patients with earlier pancreatic surgery (R = -0.57, p = 0.02). The pressure was not related to functional factors or the presence of pancreatic calcifications. In conclusion, pancreatic tissue fluid pressure is a valuable indicator of pain in chronic pancreatitis.
Databáze: OpenAIRE
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