Familial concordance for height and its components: Analyses from the breakthrough generations study
| Autor: | Michael Jones, Alan Ashworth, Anthony J. Swerdlow, Minouk J. Schoemaker, Danielle H. Morris |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Adolescent Concordance media_common.quotation_subject Cohort Studies Young Adult symbols.namesake Genetics Humans Medicine Poisson Distribution Poisson regression Ecology Evolution Behavior and Systematics Aged media_common Aged 80 and over Leg Daughter Anthropometry business.industry Middle Aged Trunk Body Height United Kingdom Confidence interval Anthropology Relative risk Arm symbols Arm span Regression Analysis Female Anatomy business Demography |
| Zdroj: | American Journal of Human Biology. 24:22-27 |
| ISSN: | 1042-0533 |
| DOI: | 10.1002/ajhb.21230 |
| Popis: | Objectives: To assess familial resemblance for height, arm span, and components of these, and differences between concordance for short and tall heights. Methods: We examined whether female relatives were similar for six anthropometric measurements (height, arm span, leg, trunk and arm length, and leg: trunk length ratio). Subjects were 31,622 related individuals aged 16-102 yr participating in the UK Breakthrough Generations Study. Height and arm span were self-reported, limb and trunk length were measured in a subset (N = 508) by study investigators, and paternal height was reported by the daughter. Data were analyzed using correlations and Poisson regression. Results: Correlation coefficients within families were 0.4 for height, 0.3 for arm span, and 0.5 for leg length, trunk length, leg: trunk ratio, and arm length. Women had a relative risk (RR) of being short (i. e., in the lowest height quintile) of 2.3 (95% confidence interval [CI] = 2.1-2.5) if their mother was short, 2.1 (95% CI = 1.9-2.3) if their father was short, and 3.7 (95% CI = 3.4-4.0) if both parents were short. RRs of being tall (i. e., in the highest height quintile) were 2.3 (95% CI = 2.1-2.5), 2.4 (95% CI = 2.2-2.6), and 4.4 (95% CI = 4.1-4.8) if their mother, father or both were tall, respectively. Conclusions: We have shown, for the first time, that leg: trunk length ratio and arm length aggregate within families. Concordance seemed to be stronger for tall than short heights. Am. J. Hum. Biol. 24: 22-27, 2012. ' 2011Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text