Spastic co-contraction is directly associated with altered cortical beta oscillations after stroke

Autor: David Amarantini, Alexandre Chalard, David Gasq, Joseph Tisseyre, Philippe Marque
Přispěvatelé: Toulouse Neuro Imaging Center (ToNIC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], Hôpital de Rangueil, CHU Toulouse [Toulouse], GASQ, David, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Upper extremity
[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
Movement
Elbow
Brain injuries
050105 experimental psychology
03 medical and health sciences
Young Adult
0302 clinical medicine
Muscle Hypertonia
Physical medicine and rehabilitation
Physiology (medical)
Multimodal analysis
Neuroplasticity
medicine
Spastic
[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
Humans
0501 psychology and cognitive sciences
[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Beta (finance)
Muscle
Skeletal
Stroke
Aged
Cerebral Cortex
business.industry
Electromyography
Muscle hypertonia
05 social sciences
Middle Aged
medicine.disease
Sensory Systems
Co contraction
Biomechanical Phenomena
medicine.anatomical_structure
Neurology
Muscle Spasticity
Neuronal plasticity
Female
[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Neurology (clinical)
business
Beta Rhythm
030217 neurology & neurosurgery
Zdroj: Clinical Neurophysiology
Clinical Neurophysiology, Elsevier, 2020, 131 (6), pp.1345-1353. ⟨10.1016/j.clinph.2020.02.023⟩
Clinical Neurophysiology, 2020, 131 (6), pp.1345-1353. ⟨10.1016/j.clinph.2020.02.023⟩
ISSN: 1388-2457
DOI: 10.1016/j.clinph.2020.02.023⟩
Popis: Objective Spastic co-contraction is a motor-disabling form of muscle overactivity occurring after a stroke, contributing to a limitation in active movement and a certain level of motor impairment. The cortical mechanisms underlying spastic co-contraction remain to be more fully elucidated, the present study aimed to investigate the role of the cortical beta oscillations in spastic co-contraction after a stroke. Method We recruited fifteen post-stroke participants and nine healthy controls. The participants were asked to perform active elbow extensions. In the study, multimodal analysis was performed to combine the evaluation of three-dimensional elbow kinematics, the elbow muscles electromyographic activations, and the cortical oscillatory activity. Results The movement-related beta desynchronization was significantly decreased in post-stroke participants compared to healthy participants. We found a significant correlation between the movement-related beta desynchronization and the elbow flexors activation during the active elbow extension in post-stroke participants. When compared to healthy participants, post-stroke participants exhibited significant alterations in the elbow kinematics and greater muscle activation levels. Conclusions Cortical beta oscillation alterations may reflect an important neural mechanism underlying spastic co-contraction after a stroke. Significance Measuring the cortical oscillatory activity could be useful to further characterize neuromuscular plasticity induced by recovery or therapeutic interventions.
Databáze: OpenAIRE
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