Volumetric Capnography for the Evaluation of Pulmonary Disease in Adult Patients with Cystic Fibrosis and Noncystic Fibrosis Bronchiectasis

Autor: José Dirceu Ribeiro, L. Veronez, MM Moreira, Maria Angela Gonçalves de Oliveira Ribeiro, Luiz Cláudio Martins, Renato G. G. Terzi, Ilma Aparecida Paschoal, S. T. P. Soares, Mônica Corso Pereira
Rok vydání: 2010
Předmět:
Zdroj: Lung. 188:263-268
ISSN: 1432-1750
0341-2040
DOI: 10.1007/s00408-009-9213-z
Popis: This study was designed to use volumetric capnography to evaluate the breathing pattern and ventilation inhomogeneities in patients with chronic sputum production and bronchiectasis and to correlate the phase 3 slope of the capnographic curve to spirometric measurements. Twenty-four patients with cystic fibrosis (CF) and 21 patients with noncystic fibrosis idiopathic bronchiectasis (BC) were serially enrolled. The diagnosis of cystic fibrosis was based on the finding of at least two abnormal sweat chloride concentrations (iontophoresis sweat test). The diagnosis of bronchiectasis was made when the patient had a complaint of chronic sputum production and compatible findings at high-resolution computed tomography (HRCT) scan of the thorax. Spirometric tests and volumetric capnography were performed. The 114 subjects of the control group for capnographic variables were nonsmoker volunteers, who had no respiratory symptoms whatsoever and no past or present history of lung disease. Compared with controls, patients in CF group had lower SpO2 (P
Databáze: OpenAIRE