Reversible, β-sheet-dependent self-assembly of the phosphoprotein phosvitin is controlled by the concentration and valency of cations

Autor:	Martin U. Betschart, Melika Sarem, V. Prasad Shastri, Steffen Lüdeke
Rok vydání:	2022
Předmět:	Phosvitin Cations Divalent Circular Dichroism General Physics and Astronomy Protein Conformation beta-Strand Hydrogen-Ion Concentration Physical and Theoretical Chemistry Phosphoproteins Protein Structure Secondary
Zdroj:	Physical Chemistry Chemical Physics. 24:11791-11800
ISSN:	1463-9084 1463-9076
Popis:	At low pH, the hyperphosphorylated intrinsically disordered protein phosvitin undergoes a conformational transition to a β-sheet accompanied by slow protein–protein assembly. Different cations modulate this process in different ways.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f5e561b5d86b2b019450778e931cdc https://doi.org/10.1039/d1cp05493g Zobrazit plný text záznamu