Seroprevalence of Canine Parvovirus in Dogs in Lusaka District, Zambia

Autor: Saasa, Ngonda, Nalubamba, King Shimumbo, M'kandawire, Ethel, Siwila, Joyce
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Veterinary Medicine, Vol 2016 (2016)
Journal of Veterinary Medicine
ISSN: 2314-6966
2356-7708
Popis: Canine parvovirus (CPV) enteritis is a highly contagious enteric disease of young dogs. Limited studies have been done in Zambia to investigate the prevalence of CPV in dogs. Blood was collected from dogs from three veterinary clinics (clinic samples, n=174) and one township of Lusaka (field samples, n=56). Each dog’s age, sex, breed, and vaccination status were recorded. A haemagglutination assay using pig erythrocytes and modified live parvovirus vaccine as the antigen was used. Antibodies to CPV were detected in 100% of dogs (unvaccinated or vaccinated). The titres ranged from 160 to 10240 with a median of 1280. Vaccinated dogs had significantly higher antibody titres compared to unvaccinated (p<0.001). There was a significant difference in titres of clinic samples compared to field samples (p<0.0001) but not within breed (p=0.098) or sex (p=0.572). Multiple regression analysis showed that only age and vaccination status were significant predictors of antibody titres. The presence of antibody in all dogs suggests that the CPV infection is ubiquitous and the disease is endemic, hence the need for research to determine the protection conferred by vaccination and natural exposure to the virus under local conditions.
Databáze: OpenAIRE
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