Effects of supplementation of rumen-protected choline on growth performance, meat quality and gene expression in longissimus dorsi muscle of lambs

Autor:	M.Z. Wang, Shimin Liu, Qing Chen, Hongrong Wang, Lihuai Yu, Lisha Sun, Li Huawei
Rok vydání:	2015
Předmět:	medicine.medical_specialty Meat Adipose Tissue White Blood lipids Gene Expression Biology Choline chemistry.chemical_compound Rumen Animal science Internal medicine medicine Animals Muscle Skeletal Sheep Domestic Lipoprotein lipase General Veterinary Lipid metabolism General Medicine Lipid Metabolism Animal Feed Diet Endocrinology chemistry Lipogenesis Dietary Supplements Animal Science and Zoology sense organs Intramuscular fat Lipoprotein
Zdroj:	Archives of animal nutrition. 69(5)
ISSN:	1477-2817
Popis:	This study determined the effects of rumen-protected choline (RPC) on growth performance, blood lipids, meat quality and expression of genes involved in fatty-acid metabolism in young lambs. A total of 24 Dorper × Hu lambs (about 20 kg body weight) were kept in individual pens and fed diets with 0%, 0.25%, 0.50% and 0.75% RPC for 60 d. Supplementation of 0.25% RPC increased average daily gain of lambs, whereas treatments had no significant effect on feed intake. The pH values of meat were increased at 0.25% RPC and both, dripping loss and shear force of meat, were significantly decreased in RPC-supplemented lambs. No significant changes were observed for dressing percentage and intramuscular fat. RPC supplementations had no significant effect on the concentrations of triglycerides and cholesterols in serum, but the concentration of high-density lipoprotein was decreased at 0.50% RPC and that of low-density lipoprotein was increased at 0.75% RPC. In m. longissimus dorsi, the expressions of cluster of differentiation 36 (CD36), acetyl-CoA carboxylase (ACC) and fatty-acid synthase (FASN) genes were increased at 0.25% RPC. Supplementation of 0.75% RPC increased the expressions of lipoprotein lipase (LPL) and FASN genes, decreased the expression of ACC gene and had no effect on CD36 gene. The results of this study showed that supplementation of 0.25% RPC could promote growth performance of lambs and improve meat quality. This may be mediated by effects on blood lipid profiles and the metabolism of fatty acids in skeleton muscles. However, the beneficial effects of 0.25% RPC supplementation need to be validated with a larger number of animals. Higher doses, particularly 0.75% RPC, showed adverse effects on live weight gain and ACC expression.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f0702599390e97b7472dac479dc666 https://pubmed.ncbi.nlm.nih.gov/26305383 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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