A longitudinal cohort study of Finnish patients with primary Sjögren's syndrome: clinical, immunological, and epidemiological aspects
| Autor: | E Pukkala, P Laippala, M. Pertovaara, Ari Miettinen, Amos Pasternack |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Risk medicine.medical_specialty Immunology Population General Biochemistry Genetics and Molecular Biology Statistics Nonparametric Rheumatology Internal medicine Cause of Death Epidemiology medicine Immunology and Allergy Humans Longitudinal Studies education Finland Aged education.field_of_study medicine.diagnostic_test business.industry Incidence (epidemiology) Incidence Lymphoma Non-Hodgkin Odds ratio Middle Aged medicine.disease Confidence interval Surgery Lymphoma Extended Report Logistic Models Sjogren's Syndrome Erythrocyte sedimentation rate Cohort Female business beta 2-Microglobulin Biomarkers |
| Zdroj: | Annals of the rheumatic diseases. 60(5) |
| ISSN: | 0003-4967 |
| Popis: | OBJECTIVE—To evaluate outcome in a cohort of Finnish patients with primary Sjogren's syndrome (pSS). METHODS—Clinical and laboratory data from the time of diagnosis and follow up were collected from 110 patients with pSS (107 women, three men) diagnosed in 1977-1992 in central Finland. The standardised incidence ratio for cancers was determined as the ratio of the observed number of cases to the expected number based on regional population rates. Eighty one of the 93 patients still alive were interviewed, and clinical and laboratory examinations performed in 1994-1997. RESULTS—The mean (SD) erythrocyte sedimentation rate (33 (22) v 45 (28) mm/1st h), serum IgG (18.8 (7.4) v 22.5 (8.5) g/l), and serum IgM (1.6 (1.1) v 2.0 (1.2) g/l) at the control visit were significantly (p |
| Databáze: | OpenAIRE |
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