An integrative appraisal of the hormonal and metabolic changes induced by acute stress using king penguins as a model
| Autor: | Tina Cornioley, Jean-Patrice Robin, René Groscolas, Antoine Stier, Quentin Schull, Jean-Jérôme Ménard, Vincent A. Viblanc |
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| Přispěvatelé: | Département Ecologie, Physiologie et Ethologie (DEPE-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institute of Evolutionary Biology and Environmental Studies, Universität Zürich [Zürich] = University of Zurich (UZH), Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, IPEV, University of Zurich, Viblanc, Vincent A, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), University of Zürich [Zürich] (UZH) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Blood Glucose
Male 0106 biological sciences 0301 basic medicine [SDV]Life Sciences [q-bio] Fatty Acids Nonesterified 01 natural sciences Cortisol chemistry.chemical_compound Endocrinology Corticosterone Homeostasis Allostasis Seabird 1310 Endocrinology Reactive scope Models Animal [SDE]Environmental Sciences Metabolome Ketone bodies 590 Animals (Zoology) medicine.medical_specialty Biology 010603 evolutionary biology 10127 Institute of Evolutionary Biology and Environmental Studies 03 medical and health sciences Stress Physiological Internal medicine medicine Animals Lipolysis Lactic Acid Glucocorticoids Body Weight Metabolism Spheniscidae Uric Acid Kinetics 030104 developmental biology chemistry 570 Life sciences biology Uric acid Animal Science and Zoology 1103 Animal Science and Zoology Hormone |
| Zdroj: | General and Comparative Endocrinology General and Comparative Endocrinology, Elsevier, 2018, ⟨10.1016/j.ygcen.2017.08.024⟩ General and Comparative Endocrinology, Elsevier, 2017, ⟨10.1016/j.ygcen.2017.08.024⟩ |
| ISSN: | 0016-6480 1095-6840 |
| DOI: | 10.1016/j.ygcen.2017.08.024⟩ |
| Popis: | International audience; A large number of studies have focused on the reactivity of the hypothalamic-pituitaryadrenal (HPA) axis and the consequences of glucocorticoids (GC) in mediating life-history trade-offs. Although short-term increases in GCs are viewed as adaptive, mobilizing energy substrates allowing animals to deal with impending threats (e.g. stimulating hepatic gluconeogenesis, stimulating lipolysis, mobilizing amino acids), few studies have actually measured the exact time-course of substrate mobilisation in response to acute stress in natural conditions. We evaluated the hormonal and metabolic components of the stress response to acute stress in 32 free-living king penguins (Aptenodytes patagonicus). We monitored changes in blood GCs (corticosterone, CORT), glucose, lactate, ketone bodies (b-hydroxybutyrate), non-esterified fatty acids, and uric acid in response to a standardized capture-restraint protocol lasting for up to 90 min. Furthermore, we tested whether the vigilance status of the animal (alert or asleep) affected its perception of the capture, thereby modulating the hormonal and metabolic stress responses. The time course of energy mobilisation followed the characteristic pattern expected from laboratory and theoretical models, with a rapid depletion of those energy stores linked to rapid adrenergic responses (i.e. glucose and ketone bodies), followed by a mobilisation of energy stores associated with the sustained longer-term GC response (i.e. fats and protein stores). HPA reactivity was generally slower than reported in other birds, and there was high inter-individual variability. Sleeping birds had higher GC and glucose responses to acute stress, suggesting a more rapid mobilization of energy stores. Our results highlight the importance of considering HPA and metabolic responses to acute stress against species-specific life history and ecological relevant backgrounds. |
| Databáze: | OpenAIRE |
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