Fragile skin microbiomes in megacities are assembled by a predominantly niche-based process
| Autor: | Jin Ju Kim, Hyejin Kim, Johnhwan Lee, Hanbyul Kim, Ji-yei Choi, Taeyune Kim, Susun An, Eunjoo Kim, Woo Jun Sul, Taehun Park, Nu Ri Myeong |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult 030106 microbiology Niche Biology Microbiology 03 medical and health sciences Asian People Abundance (ecology) Urbanization Dominance (ecology) Humans Microbiome Cities Research Articles Skin Multidisciplinary integumentary system Bacteria Ecology Microbiota Human microbiome SciAdv r-articles Life Sciences 030104 developmental biology Megacity Female Fragile skin Research Article |
| Zdroj: | Science Advances |
| ISSN: | 2375-2548 |
| Popis: | Predominant niche-based process assembly of megacity skin microbiomes results in a relatively fragile microbial network. Given the higher incidence of skin diseases in more urbanized populations and its association with the skin microbiome, we questioned how the skin microbiome differed depending on the degree of urbanization. Skin microbiomes of 231 healthy subjects in five large cities in China varied mainly with environment and socioeconomic status of the cities in question. The differences among microbiomes could be explained by the predominantly niche-based assembly of microbial communities, which was supported by a dominance test, β-null deviation, and edge-length abundance distribution. Networks among microbes in larger cities were more fragile, which may contribute to the higher incidence of skin diseases in more urbanized environments. These results suggest that microbial ecological theory can provide a framework for understanding crucial health-associated features of the human microbiome. |
| Databáze: | OpenAIRE |
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