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KrzewickaRomaniuk Ewa, Siedlecka Dagna, Makuch Marcelina, Romaniuk Artur. Patophysiology of metabolic syndrome in mentally ill patients treated by antipsychotics. Journal of Education, Health and Sport. 2019;9(8):29-34. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.3359148 http://ojs.ukw.edu.pl/index.php/johs/article/view/7216 https://pbn.nauka.gov.pl/sedno-webapp/works/920406 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2019; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.07.2019. Revised: 25.07.2019. Accepted: 02.08.2019. Patophysiology of metabolic syndrome in mentally ill patients treated by antipsychotics Ewa Krzewicka-Romaniuk1, Dagna Siedlecka1, Marcelina Makuch2, ArturRomaniuk3 Department of Pathophysiology, Medical University of Lublin, Lublin, Poland Chair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland Praktyka Lekarza Rodzinnego “Familia” ul. Niepodległości 29, 21-040 Świdnik, Poland KEY WORDS: metabolic syndrome; antipsychotics; obesity; SGAs ABSTRACT The metabolic syndrome is increasingly named as epidemic of our time. It affects about 20-25% of the world's population and is associated with a twofold increase in the risk of death and a threefold increase in the risk of heart attack and stroke. Numerous scientific studies confirm the more frequent occurrence of the metabolic syndrome among the mentally ill patients than in the general population. It is related not only to common inflammatory etiology of psychiatric disorders and metabolic syndrome, endocrinopathies accompanying mental illness, unhealthy lifestyle of psychiatric patients or genetic predispositions of this group of patients to the development of metabolic disorders, but also with the use of psychiatric drugs such as antipsychotics or mood stabilizers.   |