Ultrastructural organization of thrombocytes in normal monkeys (Macaca arctoides) and in those with experimental viral malignant lymphoma
Autor: | G.N. Chuvirov, V.N. Fomenko |
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Rok vydání: | 1978 |
Předmět: |
Macaca arctoides
Blood Platelets Male Pathology medicine.medical_specialty Lymphoma Alpha (ethology) Biology Cytoplasmic Granules Malignant lymphoma chemistry.chemical_compound Megakaryocyte medicine Animals Humans Platelet Glycogen General Medicine Haplorhini medicine.disease biology.organism_classification Leukemia medicine.anatomical_structure Blood Retroviridae chemistry Ultrastructure Macaca Female |
Zdroj: | Experimentelle Pathologie. 15(6) |
ISSN: | 0014-4908 |
Popis: | Summary Data on platelet ultrastructure of 6 M. arctoides monkeys investigated before and during experimental viral malignant lymphoma are presented. It has been established that the inner structure of thrombocytes in healthy monkeys was almost similar to that of man. In experimental malignant lymphoma, irrespective of the clinical period of the disease, a decrease of alpha-, beta- and sigma-granules, a decrease of the functional activity of thrombocytes and an increase of delta-granules and glycogen granulation content were observed. The above mentioned disturbances can be a result of changes of megakaryocytes in malignant lymphoma. No viral particles in thrombocytes of neither healthy nor sick monkeys have been revealed. |
Databáze: | OpenAIRE |
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