Trends and influencing factors of plasma folate levels in Chinese women at mid-pregnancy, late pregnancy and lactation periods
| Autor: | Jianmeng Liu, Ying Meng, Hongtian Li, Yubo Zhou, Xiucui Li, Ke-Yi Si |
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| Rok vydání: | 2020 |
| Předmět: |
China
Sociodemographic Factors Breastfeeding Nutritional Status Medicine (miscellaneous) Physiology Lower risk Mid pregnancy Folic Acid Asian People Pregnancy Risk Factors Interquartile range Lactation medicine Humans Nutrition and Dietetics Geography business.industry medicine.disease Late pregnancy Breast Feeding Cross-Sectional Studies medicine.anatomical_structure Relative risk Female business |
| Zdroj: | British Journal of Nutrition. 126:885-891 |
| ISSN: | 1475-2662 0007-1145 |
| DOI: | 10.1017/s0007114520004821 |
| Popis: | Folate status for women during early pregnancy has been investigated, but data for women during mid-pregnancy, late pregnancy or lactation are sparse or lacking. Between May and July 2014, we conducted a cross-sectional study in 1211 pregnant and lactating women from three representative regions in China. Approximately 135 women were enrolled in each stratum by physiological periods (mid-pregnancy, late pregnancy or lactation) and regions (south, central or north). Plasma folate concentrations were measured by microbiological assay. The adjusted medians of folate concentration decreased from 28·8 (interquartile range (IQR) 19·9, 38·2) nmol/l in mid-pregnancy to 18·6 (IQR 13·2, 26·4) nmol/l in late pregnancy, and to 17·0 (IQR 12·3, 22·5) nmol/l in lactation (Pfor trend < 0·001). Overall, lower folate concentrations were more likely to be observed in women residing in the northern region, with younger age, higher pre-pregnancy BMI, lower education or multiparity, and in lactating women who had undergone a Caesarean delivery or who were breastfeeding exclusively. In total, 380 (31·4 %) women had a suboptimal folate status (folate concentration |
| Databáze: | OpenAIRE |
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