15-year experience with rotavirus vaccination in Mexico: a systematic literature review
| Autor: | Maria Yolanda Cervantes-Apolinar, Dagna Constenla, Roberto Carreño-Manjarrez, Ángel Alexis Flores, Eduardo Ortega-Barria, Adriana Guzman-Holst |
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| Rok vydání: | 2021 |
| Předmět: |
Rotavirus
Pediatrics medicine.medical_specialty 030231 tropical medicine Immunology Review immunogenicity Vaccines Attenuated Rotavirus vaccination Rotavirus Infections disease burden 03 medical and health sciences 0302 clinical medicine systematic review Intussusception (medical disorder) medicine health economics Animals Humans Immunology and Allergy 030212 general & internal medicine Mexico Disease burden intussusception Pharmacology rotavirus vaccine Health economics business.industry Immunogenicity Vaccination Rotavirus Vaccines acute diarrhea Infant medicine.disease Rotavirus vaccine rotavirus gastroenteritis Systematic review Immunization program Cattle business |
| Zdroj: | Human Vaccines & Immunotherapeutics article-version (VoR) Version of Record |
| ISSN: | 2164-554X 2164-5515 |
| Popis: | A systematic review was conducted in Mexico to consolidate and evaluate evidence after 15 years of rotavirus vaccination, according to the National Immunization Program. Five databases were screened to identify published articles (January 2000–February 2020) with evidence on all clinical and epidemiological endpoints (e.g. immunogenicity, safety, efficacy, impact/effectiveness) of rotavirus vaccination in Mexico. Twenty-two articles were identified (observational studies including health-economic models: 17; randomized controlled trials: 5). Fourteen studies evaluated a human attenuated vaccine (HRV), four studies evaluated both vaccines, and only two evaluated a bovine-human reassortant vaccine, with local efficacy data only for HRV. Local evidence shows vaccines are safe, immunogenic, efficacious, and provide an acceptable risk-benefit profile. The benefits of both vaccines in alleviating the burden of all-cause diarrhea mortality and morbidity are documented in several local post-licensure studies. Findings signify overall benefits of rotavirus vaccination and support the continued use of rotavirus vaccine in Mexico. |
| Databáze: | OpenAIRE |
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