Preliminary Study on Antibacterial Activity of Sawo Kecik (Manilkara kauki (L.) Dubard) Roots Extract

Autor: Sitoresmi Prabaningtyas, Novida Pratiwi, Rini Retnosari
Rok vydání: 2021
Předmět:
Zdroj: Jurnal Biodjati, Vol 6, Iss 1, Pp 146-152 (2021)
ISSN: 2548-1606
2541-4208
DOI: 10.15575/biodjati.v6i1.7708
Popis: The roots of sawo kecik (Manilkara kauki (L.) Dubard) contai n astringent that can be used to treat diarrhea for infants. However, the active antibacterial substance in sawo kecik roots has not been known. Therefore, the research to understand the antimicrobial activity of sawo kecik roots extract against Escherichia coli and Staphylococcus aureus was performed. Sawo kecik roots were macerated using methanol and chloroform. The result was then treated with E.coli and S.aureus with a concentration of 5 ppm and compared to negative control (solvent) and further observed and analyzed how reduced the bacterial growth with Two Ways ANOVA without interaction . The research result s indicated that the sawo kecik roots methanol extract was effective to slow down the growth of S.aureus ( 0.160 ± 0.007) but ineffective against E.coli , w hereas sawo kecik roots chloroform extract was not effective to reduce both bacteria. It can be concluded that further research is required to measure and verify the antibacterial activity of the extract using higher concentration samples and different research methodology.
Databáze: OpenAIRE