Survey of the occurrence of adenosine polyphosphatase in extracellular matrix of rat tissues
| Autor: | Dharamdajal Kalicharan, Mj Hardonk, Ww Bakker, C.E. Hulstaert, Klaas Poelstra |
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| Rok vydání: | 1991 |
| Předmět: |
Male
Cytoplasm Histology Duodenum Kidney Glomerulus Submandibular Gland Inflammation Biology Extracellular matrix Macrophages Alveolar Extracellular medicine Animals Molecular Biology Adenosine Triphosphatases Kidney Salivary gland Histocytochemistry Apyrase Rats Inbred Strains Cell Biology General Medicine Adenosine Capillaries Extracellular Matrix Rats Cell biology Microscopy Electron Medical Laboratory Technology medicine.anatomical_structure Liver Biochemistry Choroid plexus Anatomy medicine.symptom General Agricultural and Biological Sciences medicine.drug |
| Zdroj: | Histochemistry. 96:441-447 |
| ISSN: | 1432-119X 0301-5564 |
| DOI: | 10.1007/bf00316002 |
| Popis: | The extracellular presence of adenosine polyphosphatase was investigated in a number of rat tissues. The enzyme was demonstrated in basement membranes of epithelial cells of duodenum, urinary bladder, tongue, choroid plexus, submandibular salivary gland, lung and kidney, as well as in basement membranes of capillaries in these tissues. Furthermore adenosine polyphosphatase was demonstrated on collagen fibrils and in the cytoplasm of fibroblasts of all investigated tissues. It appears that the presence of adenosine polyphosphatase in basement membranes is a widespread phenomenon. Since extracellular ADP and ATP are known to promote respectively platelet aggregation and inflammation, the presence of extracellular ADP and ATP-hydrolyzing activity might contribute to inhibit these processes. |
| Databáze: | OpenAIRE |
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