Cutaneous manifestations of Castleman disease
| Autor: | Jorge Ocampo-Candiani, Alejandra Villarreal-Martinez, Minerva Gómez-Flores, Osvaldo Vázquez-Martínez, Sonia Chavez-Alvarez, Gloria González-Saldivar, Maira Elizabeth Herz-Ruelas |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Paraneoplastic Syndromes MEDLINE Dermatology Disease Lymphoid hyperplasia 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Humans Vascular proliferation Lymphatic Diseases Skin manifestations business.industry Castleman Disease Castleman disease medicine.disease Lymphoproliferative Disorders Paraneoplastic pemphigus 030220 oncology & carcinogenesis Physical exam medicine.symptom business Pemphigus |
| Zdroj: | International Journal of Dermatology. 59:1226-1240 |
| ISSN: | 1365-4632 0011-9059 |
| Popis: | Background Castleman disease (CD) is a lymphoproliferative B-cell disease that is diagnosed from lymphoid hyperplasia with vascular proliferation. Symptoms may include fever, night sweats, and weight loss. Cutaneous manifestations often may go unnoticed since little has been described in the literature regarding them. Materials and methods A search of CD with cutaneous manifestations was performed in PUBMED, ProQuest, Ovid, Scopus, EMBASE, and Medline. All articles included patients over 18 years of age with a diagnosis of CD and cutaneous manifestations. Results A total of 68 articles were included. The most common cutaneous manifestations include paraneoplastic pemphigus and erythematous-brown plaques, papules, or nodules. Patients presenting with these manifestations should always have a thorough physical exam, and clinicians should try to identify any palpable lymph nodes. A complete workup to rule out other neoplasias needs to be performed as well. Conclusions A better understanding of these skin manifestations of CD may help physicians promptly diagnose and reconsider the path of diagnostic tests to identify this entity. |
| Databáze: | OpenAIRE |
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