Association of serum uric acid with 2-hour postload glucose in Chinese with impaired fasting plasma glucose and/or HbA1c
| Autor: | Tao Yang, Yuan Gao, Min Sun, Yue-Hua Qin, Qi Fu, Hongqi Fan, Su-Juan Wang, Mei Zhang, Wei Tang, Hongwen Zhou, Zhixiao Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Blood Glucose
Male Anatomy and Physiology endocrine system diseases Epidemiology Uric acid blood chemistry.chemical_compound Endocrinology Sex factors Risk Factors Odds Ratio Insulin Glucose tolerance test Plasma glucose Multidisciplinary medicine.diagnostic_test Fasting Middle Aged Medicine Female Research Article medicine.medical_specialty China Clinical Research Design Science Endocrine System Sex Factors Asian People Internal medicine Glucose Intolerance medicine Humans Biology Aged Diabetic Endocrinology Glycated Hemoglobin Endocrine Physiology Population Biology business.industry Serum uric acid nutritional and metabolic diseases Diabetes Mellitus Type 2 Glucose Tolerance Test Uric Acid chemistry Uric acid business |
| Zdroj: | PLoS ONE, Vol 8, Iss 7, p e67759 (2013) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | ObjectiveTo examine whether serum uric acid (SUA) is associated with 2-hour postload glucose (2-h PG) in Chinese with impaired fasting plasma glucose (IFG) and/or HbA1c (IA1C).Research design and methodsAnthropometric and biochemical examinations, such as SUA concentration, were performed in 3763 individuals from all the villages in Baqiao County, China. A 75-g oral glucose tolerance test (OGTT) was conducted in 1197 Chinese with prediabetes as having IFG (110 ≤ fasting plasma glucose [FPG] ResultsThe present study included 1197 participants with IFG and/or IA1C (mean age 56.5 ± 10.3 years; 50.6% men). In multivariate linear regression, after adjustment for gender, age, smoking and drinking, body mass index (BMI), systolic and diastolic blood pressure (SBP, DBP), lipid profiles, logarithmic transformed C-reactive protein (log-CRP), estimated glomerular filtration rate (e-GFR), FPG and HbA1c, with a 1-mg/dl increment of SUA, 2-h PG increased by 5.04 ± 0.72 (PConclusionsSUA is significantly associated with 2-h PG in Chinese with IFG and/or IA1C. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|