Anti-tubulin immunohistochemistry study of Echinococcus granulosus protoscolices incubated with albendazole and albendazole sulphoxide in vitro
| Autor: | N. Casado, G. Bodega, Jorge Pérez-Serrano, Filomena Rodriguez-Caabeiro, Guillermo Maria Denegri |
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| Rok vydání: | 1995 |
| Předmět: |
Pathology
medicine.medical_specialty Metabolite Cestoda Antibodies Helminth macromolecular substances Albendazole chemistry.chemical_compound Tubulin parasitic diseases medicine Parasite hosting Animals Anthelmintic Echinococcus granulosus Sheep General Veterinary biology General Medicine biology.organism_classification Molecular biology Immunohistochemistry In vitro Echinococcus Infectious Diseases chemistry Insect Science biology.protein Parasitology Cattle medicine.drug |
| Zdroj: | Parasitology research. 81(5) |
| ISSN: | 0932-0113 |
| Popis: | Tubulin content was immunohistochemically studied in Echinococcus granulosus protoscolices incubated with albendazole and albendazole sulphoxide alone or in combination. Tubulin immunoreactivity was very patent in the control protoscolices and was mainly located in the sucker region and the invagination channel of protoscolices. Treated protoscolices always showed less immunoreactivity than did control protoscolices. We concluded that albendazole and its metabolite albendazole sulphoxide produce tubulin alterations in E. granulosus protoscolices. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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