Diffuse Neurofibroma in a Patient with Unknown History of NF1

Autor: Khaled M. Hindi, Mishal M. AlMutairi, Jassem Bastaki, Mahmoud A. K. Ebrahim
Rok vydání: 2018
Předmět:
Zdroj: Case Reports in Otolaryngology, Vol 2018 (2018)
Case Reports in Otolaryngology
ISSN: 2090-6773
2090-6765
DOI: 10.1155/2018/8768472
Popis: Malignant peripheral nerve sheath tumor (MPNST) is a rare disease in the parotid gland with a poor prognosis in most cases. The disease most often develops in the setting of neurofibromatosis type 1 (NF1) but can also occur sporadically. Herein, we report a rare case of MPNST in the parotid gland, in a patient with no previous history of NF1. Initial investigations of the patient, which consisted of laboratory investigations, ultrasound imaging of the swelling, fine-needle aspiration (FNA), computed tomography (CT) scan, and magnetic resonance imaging (MRI) of the neck and swelling, were compatible with a benign pleomorphic adenoma of the parotid gland. However, intraoperatively, the dissection was challenging as the tumor was adherent to the neighboring tissue. A diagnosis of MPNST arising from a diffuse neurofibroma was established based on clinicopathologic features of the disease. The patient, who exhibited clinical features compatible with (NF1), proceeded for radiotherapy following surgery to continue his treatment.
Databáze: OpenAIRE
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