Nonuniform Distribution of Occult Blood in Feces

Autor:	Richard E. Rosenfield, Zygmunt Kaczera, Jonathan Maimon, Shaul Kochwa
Rok vydání:	1979
Předmět:	Pathology medicine.medical_specialty Erythrocytes Rh-Hr Blood-Group System Specific test Fecal occult blood Autologous blood Physiology General Medicine Biology Occult Chromium Radioisotopes Feces Melena Neutralization Tests Occult Blood Colonic Neoplasms medicine Humans Ingestion Serologic Tests
Zdroj:	American Journal of Clinical Pathology. 71:204-209
ISSN:	1943-7722 0002-9173
Popis:	Inhibition of anti-Rh29 by erythrocytic stroma in feces was devised as a specific test for fecal occult blood. The sensitivity of this test was equivalent to that of a standard Hemoccult® test, namely, 108 erythrocytes/g feces. Comparison of results of this test with results of Hemoccult tests of random stool specimens and of stools following ingestion of autologous blood revealed nonuniform distribution of occult blood in feces. The extent of nonuniformity was determined by testing samples of stool specimens following ingestion of 51Cr-labeled autologous blood. This allowed comparison of Hemoccult, inhibition of anti-Rh, and radioactivity, and showed that the three labels could separate in the feces and that some single small samples of feces could be relatively free of blood while blood was readily demonstrable in other portions. The variability of a standard Hemoccult test was somewhat reduced by dispersing the feces in distilled water before performing the test.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bbb0af77ee0f0792a82c03297014a9 https://doi.org/10.1093/ajcp/71.2.204 Zobrazit plný text záznamu