Management of toxic epidermal necrolysis and related syndromes
Autor: | N Craven, Y Mukasa |
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Rok vydání: | 2008 |
Předmět: |
medicine.medical_specialty
business.industry Plasmapheresis General Medicine Controlled studies Prognosis medicine.disease Dermatology Toxic epidermal necrolysis Adrenal Cortex Hormones Renal Dialysis Epidermal necrosis Sepsis Stevens-Johnson Syndrome Humans Medicine Steroids Drug reaction business Immunosuppressive Agents |
Zdroj: | Postgraduate Medical Journal. 84:60-65 |
ISSN: | 1469-0756 0032-5473 |
DOI: | 10.1136/pgmj.2007.061465 |
Popis: | Toxic epidermal necrolysis and Stevens–Johnson syndrome are rare and life-threatening diseases that often configure as medical emergencies. The majority of cases are drug reactions. The clinical picture is one of widespread epidermal necrosis and mucosal erosions. Treatment is largely supportive and must be provided in an appropriate environment. The role of steroids and other potential disease-modifying therapies has yet to be fully established by controlled studies. The significant mortality associated with these conditions dictates that an understanding of these conditions is essential for all doctors. |
Databáze: | OpenAIRE |
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