Management of toxic epidermal necrolysis and related syndromes

Autor: N Craven, Y Mukasa
Rok vydání: 2008
Předmět:
Zdroj: Postgraduate Medical Journal. 84:60-65
ISSN: 1469-0756
0032-5473
DOI: 10.1136/pgmj.2007.061465
Popis: Toxic epidermal necrolysis and Stevens–Johnson syndrome are rare and life-threatening diseases that often configure as medical emergencies. The majority of cases are drug reactions. The clinical picture is one of widespread epidermal necrosis and mucosal erosions. Treatment is largely supportive and must be provided in an appropriate environment. The role of steroids and other potential disease-modifying therapies has yet to be fully established by controlled studies. The significant mortality associated with these conditions dictates that an understanding of these conditions is essential for all doctors.
Databáze: OpenAIRE