Impact of drugs on hypoglycaemia in hospitalised patients
| Autor: | Mathias Maitrejean, Laurent Christin, Nicolas Schaad, Frederik Vandenberghe, Corinne Challet |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Polypharmacy
Geriatrics medicine.medical_specialty Pediatrics Clinical pharmacology business.industry Logistic regression 030226 pharmacology & pharmacy law.invention Regional hospital Clinical pharmacy 03 medical and health sciences 0302 clinical medicine law Hospital admission Medicine Original Article In patient 030212 general & internal medicine General Pharmacology Toxicology and Pharmaceutics business |
| Zdroj: | Eur J Hosp Pharm |
| ISSN: | 2047-9964 2047-9956 |
| Popis: | OBJECTIVES: Hospital admission rates for hypoglycaemia now exceed those for hyperglycaemias among older adults. A growing number of reports associating hypoglycaemia with non-antidiabetic drugs have been published. Clinical pharmacists are often faced with hypoglycaemia in patients taking multiple medications. This study assessed the potential relationship between prescribed drugs and episodes of hypoglycaemia during hospitalisation. METHODS: Point-of-care blood glucose values and prescribed drugs were analysed in patients admitted to a regional hospital. Hypoglycaemia cases were defined as patients with at least one hypoglycaemic event (random glucose value ≤3.9 mmol/L), and normoglycaemic cases as those with random glucose concentrations within the range of 4.5–5.8 mmol/L. Analyses were carried out using multivariate logistic regressions and Cox proportional hazard models. RESULTS: 373 patients (53% males; median age=74 years) were included in the analysis and of these, 64 (17%) had at least one hypoglycaemic event. Patients who experienced a hypoglycaemic event had a longer length of stay (median=10 vs 7 days, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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