Low serum T3 levels are associated with false-positive results when using the risk of ovarian malignancy algorithm (ROMA) in women with benign ovarian disease
| Autor: | Dae Woo Lee, Jae Eun Shin, Hae-il Park, Min Jeong Kim, Hae Nam Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
endocrine system diseases Pelvic mass Carcinoma Ovarian Epithelial Risk Assessment lcsh:Gynecology and obstetrics Ovarian disease Ovarian tumor WAP Four-Disulfide Core Domain Protein 2 The risk of ovarian malignancy algorithm (ROMA) Ovarian cancer Biomarkers Tumor medicine Humans Predictive value of tests False Positive Reactions In patient Ovarian Diseases Ovarian malignancy Early Detection of Cancer lcsh:RG1-991 Ovarian Neoplasms business.industry Medical record Obstetrics and Gynecology nutritional and metabolic diseases Middle Aged medicine.disease female genital diseases and pregnancy complications nervous system diseases CA-125 Antigen Triiodothyronine Female business Algorithm Algorithms Glomerular Filtration Rate |
| Zdroj: | Taiwanese Journal of Obstetrics & Gynecology, Vol 60, Iss 1, Pp 36-40 (2021) |
| ISSN: | 1028-4559 |
| Popis: | Objective: We investigated factors that could cause false-positive results when using the risk of ovarian malignancy algorithm (ROMA) for assessing ovarian cancer risk. Materials and methods: ROMA scores were calculated from patients followed surgery to remove a pelvic mass. We compared a false-positive group with a true-negative group of ROMA scores. Results: We analyzed 324 patients using medical records. There were 22 with an epithelial ovarian cancer (EOC), 15 with a borderline ovarian tumor, and 287 with benign disease. Twenty-nine (10.1%) of the patients with benign disease showed high-risk ROMA score (false positive) and 13/37 (35%) patients with EOC, or borderline ovarian tumor showed low ROMA scores (false negatives). The median serum triiodothyronine (T3) level of the false-positive ROMA group in patients with benign disease was lower than in the true-negative ROMA group (p |
| Databáze: | OpenAIRE |
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