Updates on the use of liposomes for active tumor targeting in cancer therapy
| Autor: | Sharon Sy Leung, Kenneth Kw To, Wei Yan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Tumor targeting
Cancer chemotherapy Biomedical Engineering Cancer therapy Medicine (miscellaneous) Antineoplastic Agents Bioengineering 02 engineering and technology Development 03 medical and health sciences Drug Delivery Systems Neoplasms Humans Medicine General Materials Science 030304 developmental biology Drug Carriers 0303 health sciences Liposome Low toxicity business.industry Cancer 021001 nanoscience & nanotechnology medicine.disease Anticancer drug Liposomes Cancer research Nanocarriers 0210 nano-technology business |
| Zdroj: | Nanomedicine. 15:303-318 |
| ISSN: | 1748-6963 1743-5889 |
| DOI: | 10.2217/nnm-2019-0308 |
| Popis: | In the development of cancer chemotherapy, besides the discovery of new anticancer drugs, a variety of nanocarrier systems for the delivery of previously developed and new chemotherapeutic drugs have currently been explored. Liposome is one of the most studied nanocarrier systems because of its biodegradability, simple preparation method, high efficacy and low toxicity. To make the best use of this vehicle, a number of multifunctionalized liposomal formulations have been investigated. The objective of this review is to summarize the current development of novel active targeting liposomal formulations, and to give insight into the challenges and future direction of the field. The recent studies in active targeting liposomes suggest the great potential of precise targeted anticancer drug delivery in cancer therapeutics. |
| Databáze: | OpenAIRE |
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