Automated macular segmentation with spectral domain optical coherence tomography in the fellow eyes of patients with unilateral retinal vein occlusion
| Autor: | Osman Parca, Kerem Bozkurt, Gökhan Pekel, Ebru Nevin Çetin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male Retinal Ganglion Cells genetic structures retrospective study Nerve fiber layer retinal pigment epithelium Retinal Pigment Epithelium systemic disease Female Follow-Up Studies Humans Macula Lutea/*pathology Middle Aged Nerve Fibers/pathology Retinal Ganglion Cells/*pathology Retinal Pigment Epithelium/*pathology Retinal Vein Occlusion/*diagnosis Retrospective Studies Tomography Optical Coherence/*methods Retinal vein occlusion retinal outer plexiform layer chemistry.chemical_compound 0302 clinical medicine Nerve Fibers middle aged Macula Lutea image segmentation retinal thickness adult epiretinal membrane retinal inner plexiform layer Ganglion diabetic retinopathy medicine.anatomical_structure female spectral domain optical coherence tomography risk factor central macular thickness eye examination retina macula lutea nerve cell Tomography Optical Coherence visual field medicine.medical_specialty Retinal Vein Retinal layers macular degeneration optic disk Macular segmentation Article 03 medical and health sciences Ophthalmology medicine follow up controlled study human nerve fiber procedures Ganglion cell layer parametric test Retina Retinal pigment epithelium macular edema optical coherence tomography business.industry retinal nerve fiber layer Retinal fluorescence angiography Inner plexiform layer major clinical study photoreceptor eye diseases 030104 developmental biology glaucoma chemistry retina vein occlusion unilateral retinal vein occlusion retina ganglion cell 030221 ophthalmology & optometry pathology sense organs business Retinal thickness intraocular pressure |
| Popis: | Purpose: To assess the change in the macular layers in the fellow eyes of unilateral retinal vein occlusion (RVO) patients and to evaluate whether certain layers are more affected based on RVO type. Methods: This retrospective study included 87 fellow eyes of patients with unilateral RVO (26 central, 61 branch) and 105 eyes of 105 subjects without RVO. Spectral domain optical coherence tomography was used for automatized retinal segmentation. The thicknesses of retinal nerve fiber layer (RNFL), ganglion cells, inner plexiform, inner nuclear, outer plexiform, outer nuclear, photoreceptor layers, overall inner retinal layers and retinal pigment epithelium (RPE) were documented. Results: Inner plexiform layer was thinner in inferior sector in RVO group compared with the control group (p = 0.047). The subgroup analysis showed that the retina was thinner in RVO group compared with the controls without systemic diseases in some sectors of the following layers: inferior retina, RNFL, ganglion cell layer, inner plexiform layer, inner retinal layers and RPE (p < 0.05). Retinal thickness was decreased in the fellow eyes of branch RVO group compared to that in the central RVO group in the some sectors (p < 0.05). Conclusions: The fellow eyes of unilateral RVO patients did not show major structural differences compared with the controls; however, they revealed significant sectoral thinning in many retinal layers when compared with the eyes of healthy subjects without systemic diseases. Central macula was thinner in the fellow eyes of patients with branch RVO compared to that in central RVO. © 2018, Springer Nature B.V. |
| Databáze: | OpenAIRE |
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