Pathological diversity in schwannomas of the orofacial region

Autor:	Rewa Malhotra, Priya Kumar, Kiran Jot, Aadithya B Urs, Jeyaseelan Augustine
Rok vydání:	2021
Předmět:	Verocay bodies Neurilemoma Pathology medicine.medical_specialty business.industry Case Report intraosseous schwannoma General Medicine Antoni A and Antoni B areas Schwannoma medicine.disease Benign tumor Lesion otorhinolaryngologic diseases medicine Immunohistochemistry Ancient schwannoma medicine.symptom Differential diagnosis Intraosseous schwannoma business Pathological S-100 protein
Zdroj:	Asian Journal of Neurosurgery
ISSN:	2248-9614 1793-5482
DOI:	10.4103/ajns.ajns_470_20
Popis:	Schwannoma is a slow-growing, encapsulated benign tumor of the neuroectodermal origin arising from the perineural Schwann cells. This study aims to elucidate the clinicoradiographical and histopathological features of orofacial schwannomas through a case series of seven cases. The patients' aged ranged from 13 to 45 years, with a male predilection in the ratio of 5:2. One intraosseous case presented as a radiolucent lesion. All the cases exhibited Antoni A and Antoni B type of microscopic patterns in varying amounts. One case of ancient schwannoma showed degenerative features. The tumor cells showed diffuse positive immunohistochemical reaction for S-100 protein. Our study suggests that intraosseous schwannoma should be considered in the differential diagnosis of the intraosseous jaw lesions. Histopathologically, it is important to recognize the findings of ancient schwannoma and to avoid misdiagnosing it as a malignant lesion.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958ab7f1eec8f489d1d805014392c29d https://doi.org/10.4103/ajns.ajns_470_20 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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