Asymptomatic bacteriuria among the patients of type 2 diabetes mellitus

Autor:	Divya Soin, Ravinder Garg, Neerja Jindal, Sarabjot Kaur, Sumit Pal Singh Chawla, Aman Bharti, Sandeep Kumar
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Imipenem medicine.medical_specialty Antibiotic susceptibility type 2 diabetes mellitus Urinary system Antibiotic sensitivity Population lcsh:Medicine 030209 endocrinology & metabolism law.invention 03 medical and health sciences 0302 clinical medicine law Diabetes mellitus Internal medicine Medicine 030212 general & internal medicine education education.field_of_study uro-pathogens business.industry lcsh:R Type 2 Diabetes Mellitus asymptomatic bacteriuria medicine.disease Gram staining Nitrofurantoin Original Article business medicine.drug
Zdroj:	Journal of Family Medicine and Primary Care, Vol 8, Iss 2, Pp 539-543 (2019) Journal of Family Medicine and Primary Care
ISSN:	2249-4863
Popis:	Background: Asymptomatic bacteriuria (ASB) is common in neonates, preschool children, pregnant women, elderly, diabetics, catheterized patients, and patients with abnormal urinary tracts or renal diseases. Though there is currently no consensus on treatment of ASB in various population groups, it is advisable to treat the same in patients with diabetes mellitus (DM). Aims: To determine the prevalence of ASB in patients with type 2 DM and to study the spectrum of uro-pathogens causing ASB along with their antibiotic susceptibility profile. Settings and Design: This prospective, observational study was conducted in the department of Medicine of a tertiary care teaching hospital. Methods: The study was conducted on 100 patients with type 2 DM. Urine wet mount and gram stain examination was done for all to detect the presence of pus cells and bacteria in urine. Antibiotic sensitivity testing was performed in patients with significant bacteriuria to determine the sensitivity profile of isolated uro-pathogens. The data were analyzed to determine the association between diabetes and ASB. Results: ASB was common among diabetics, as evident by a prevalence of 21%. Presence of ASB showed positive correlation with poor glycemic control. Escherichia coli (E. coli) was the most common organism causing ASB followed by Candida, Pseudomonas, Klebsiella, and Citrobacter. E. coli isolated from study patients was most sensitive to imipenem and nitrofurantoin (NFT). Conclusions: ASB is common among diabetics, with poor glycemic control being a significant risk factor. E. coli is the most common organism causing ASB in diabetics, and it is most sensitive to imipenem and NFT.
Databáze:	OpenAIRE
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