Pegaspargase: Two Pediatric Case Studies of Delayed Urticaria Preceding Anaphylactic Reactions Postadministration
| Autor: | Kathleen R Busack |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pegaspargase
Pediatrics medicine.medical_specialty Chemotherapy Urticaria business.industry Lymphoblastic Leukemia medicine.medical_treatment Anaphylactic reactions medicine.disease Polyethylene Glycols Drug Hypersensitivity Chemotherapy Drugs Asparaginase Humans General Earth and Planetary Sciences Medicine Advanced Practice Nurses Child business Anaphylaxis General Environmental Science medicine.drug |
| Zdroj: | Clinical Journal of Oncology Nursing. 25:511-513 |
| ISSN: | 1538-067X 1092-1095 |
| DOI: | 10.1188/21.cjon.511-513 |
| Popis: | Pegaspargase, a chemotherapy drug known to improve survival outcomes in acute lymphoblastic leukemia, is associated with a risk for hypersensitivity reactions. At a children's hospital in the midwestern United States, two patients developed unusual reactions consisting of disseminated urticaria about two weeks after their second dose of pegaspargase. Both patients then proceeded to have severe anaphylaxis with the third dose of pegaspargase. These cases highlight the importance of advanced practice nurses being alert for the occurrence of unusual and delayed reactions to chemotherapy administration. |
| Databáze: | OpenAIRE |
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