Chlamydia and atherosclerotic coronary arterial disease in Turkey
| Autor: | Tevfik Tezcaner, Çiğdem Güngör, Leyla Cinel, Aykut Ozkul, Cem Yorgancioglu, Kaya Süzer, Mustafa Kahraman, Murat Özsan |
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| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Pathology Turkey medicine.medical_treatment Fluorescent Antibody Technique Coronary Artery Disease Gastroenterology Polymerase Chain Reaction Coronary artery disease Risk Factors Internal medicine Diabetes mellitus medicine Humans Chlamydiaceae Myocardial infarction Family history Endarterectomy Chlamydia biology business.industry General Medicine Chlamydia Infections Chlamydophila pneumoniae Middle Aged medicine.disease biology.organism_classification medicine.anatomical_structure Female Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | Acta cardiologica. 55(5) |
| ISSN: | 0001-5385 |
| Popis: | Objective - Chlamydia pneumoniae, which is a Gram(-) intracellular bacteria, besides being a respiratory pathogen, is thought to play an active role in the progress of acute myocardial infarction and chronic coronary artery disease. In this study we aim to determine the frequency of C. pneumoniae in coronary artery lesions of Turkish people. Methods and Results - The atherosclerotic material taken from 8 cases by directional atherectomy and from 23 cases by surgical endarterectomy and examined by indirect immunofluorescence (IIFA) test and polymerase chain reaction (PCR). C. pneumoniae positivity was 32.3% (10/31) by IIFA and 29.0% (9/31) by PCR while the evaluation of the methods together yield a positivity of 35.5% (11/31). Conclusions - A statistically significant difference could not be etablished between C. pneumoniae positive and negative groups according to age and the classical atherosclerotic risk factors such as diabetes mellitus, smoking, hypercholesterolaemia, hypertension, family history; besides, a statistically significant difference could not be found between the presence of C. pneumoniae and the severity and clinical picture of coronary artery disease. |
| Databáze: | OpenAIRE |
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